ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AG9 Class: NOTE 2.750%10/0

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 6,246,000 Value ($000) $13,987 Avg Close — Range —
Q2 2016
Shares 6,246,000 Value ($000) $9,422 Avg Close — Range —
Q3 2014
Shares 24,500,000 Value ($000) $59,352 Avg Close — Range —
Q2 2014
Shares 28,000,000 Value ($000) $61,616 Avg Close — Range —
Q1 2014
Shares 54,440,000 Value ($000) $146,409 Avg Close — Range —
Q4 2013
Shares 59,500,000 Value ($000) $148,034 Avg Close — Range —
Q3 2013
Shares 54,000,000 Value ($000) $126,349 Avg Close — Range —