ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AJ3 Class: NOTE 1.000%11/1

Metropolitan Life Insurance Co/NY's Holding History (CIK: 0000728618)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 690,000 Value ($000) $703 Avg Close — Range —
Q3 2016
Shares 1,385,000 Value ($000) $1,296 Avg Close — Range —