ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AJ3 Class: NOTE 1.000%11/1

WELLINGTON MANAGEMENT GROUP LLP's Holding History (CIK: 0000902219)

Note: Option positions (PUT/CALL) are excluded.

Q4 2020
Shares 280,000 Value ($000) $303 Avg Close — Range —
Q3 2020
Shares 280,000 Value ($000) $289 Avg Close — Range —
Q2 2020
Shares 280,000 Value ($000) $309 Avg Close — Range —
Q1 2020
Shares 355,000 Value ($000) $360 Avg Close — Range —
Q4 2019
Shares 715,000 Value ($000) $817 Avg Close — Range —
Q3 2019
Shares 715,000 Value ($000) $816 Avg Close — Range —
Q2 2019
Shares 715,000 Value ($000) $845 Avg Close — Range —
Q1 2019
Shares 615,000 Value ($000) $832 Avg Close — Range —
Q4 2018
Shares 1,805,000 Value ($000) $1,931 Avg Close — Range —
Q3 2018
Shares 1,805,000 Value ($000) $1,896 Avg Close — Range —
Q2 2018
Shares 2,035,000 Value ($000) $1,999 Avg Close — Range —
Q1 2018
Shares 2,035,000 Value ($000) $2,010 Avg Close — Range —
Q4 2017
Shares 2,035,000 Value ($000) $2,149 Avg Close — Range —
Q3 2017
Shares 1,775,000 Value ($000) $1,875 Avg Close — Range —
Q2 2017
Shares 1,435,000 Value ($000) $1,522 Avg Close — Range —
Q1 2017
Shares 1,000,000 Value ($000) $964 Avg Close — Range —