ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AJ3 Class: NOTE 1.000%11/1

ADVENT CAPITAL MANAGEMENT /DE/'s Holding History (CIK: 0001097278)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021
Shares 2,000 Value ($000) $2 Avg Close — Range —
Q1 2021
Shares 2,000 Value ($000) $2 Avg Close — Range —
Q3 2020
Shares 7,777,000 Value ($000) $8,064 Avg Close — Range —
Q2 2020
Shares 7,159,000 Value ($000) $7,883 Avg Close — Range —
Q1 2020
Shares 5,283,000 Value ($000) $5,301 Avg Close — Range —
Q4 2019
Shares 265,000 Value ($000) $304 Avg Close — Range —
Q3 2019
Shares 17,756,000 Value ($000) $20,261 Avg Close — Range —
Q2 2019
Shares 10,746,000 Value ($000) $12,751 Avg Close — Range —
Q1 2019
Shares 12,649,000 Value ($000) $17,103 Avg Close — Range —
Q4 2018
Shares 44,032,000 Value ($000) $47,388 Avg Close — Range —
Q3 2018
Shares 71,231,000 Value ($000) $75,071 Avg Close — Range —
Q2 2018
Shares 67,450,000 Value ($000) $66,181 Avg Close — Range —
Q1 2018
Shares 48,598,000 Value ($000) $48,198 Avg Close — Range —
Q4 2017
Shares 28,544,000 Value ($000) $30,156 Avg Close — Range —
Q3 2017
Shares 38,030,000 Value ($000) $40,330 Avg Close — Range —
Q2 2017
Shares 40,312,000 Value ($000) $42,924 Avg Close — Range —
Q1 2017
Shares 71,584,000 Value ($000) $69,095 Avg Close — Range —
Q4 2016
Shares 64,541,000 Value ($000) $65,482 Avg Close — Range —
Q3 2016
Shares 70,972,000 Value ($000) $66,281 Avg Close — Range —
Q2 2016
Shares 70,827,000 Value ($000) $50,346 Avg Close — Range —
Q1 2016
Shares 81,578,000 Value ($000) $74,545 Avg Close — Range —
Q4 2015
Shares 53,683,000 Value ($000) $59,882 Avg Close — Range —