ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AJ3 Class: NOTE 1.000%11/1

OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AM's Holding History (CIK: 0001132716)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 7,500,000 Value ($000) $7,605,000 Avg Close — Range —
Q3 2016
Shares 1,000,000 Value ($000) $933,000 Avg Close — Range —
Q2 2016
Shares 1,000,000 Value ($000) $709,000 Avg Close — Range —