ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AJ3 Class: NOTE 1.000%11/1

Empyrean Capital Partners, LP's Holding History (CIK: 0001317195)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 7,400,000 Value ($000) $10,004 Avg Close — Range —
Q4 2018
Shares 8,695,000 Value ($000) $9,336 Avg Close — Range —
Q3 2018
Shares 16,195,000 Value ($000) $17,093 Avg Close — Range —
Q2 2018
Shares 15,500,000 Value ($000) $15,221 Avg Close — Range —
Q1 2018
Shares 7,500,000 Value ($000) $7,430 Avg Close — Range —
Q4 2017
Shares 7,500,000 Value ($000) $7,917 Avg Close — Range —
Q4 2015
Shares 5,000,000 Value ($000) $5,639 Avg Close — Range —