ISIS PHARMACEUTICALS INC DEL

CUSIP: 464337AJ3 Class: NOTE 1.000%11/1

Bank of New York Mellon Corp's Holding History (CIK: 0001390777)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 900,000 Value ($000) $1,030 Avg Close — Range —
Q3 2019
Shares 900,000 Value ($000) $1,026 Avg Close — Range —
Q2 2019
Shares 900,000 Value ($000) $1,068 Avg Close — Range —
Q1 2019
Shares 900,000 Value ($000) $1,217 Avg Close — Range —
Q4 2018
Shares 400,000 Value ($000) $431 Avg Close — Range —
Q3 2018
Shares 900,000 Value ($000) $947 Avg Close — Range —
Q2 2018
Shares 900,000 Value ($000) $882 Avg Close — Range —
Q1 2018
Shares 1,200,000 Value ($000) $1,190 Avg Close — Range —
Q4 2017
Shares 1,200,000 Value ($000) $1,266 Avg Close — Range —
Q3 2017
Shares 1,200,000 Value ($000) $1,273 Avg Close — Range —
Q2 2017
Shares 1,200,000 Value ($000) $1,272 Avg Close — Range —
Q1 2017
Shares 1,200,000 Value ($000) $1,154 Avg Close — Range —
Q4 2016
Shares 1,350,000 Value ($000) $1,395 Avg Close — Range —
Q3 2016
Shares 450,000 Value ($000) $420 Avg Close — Range —
Q2 2016
Shares 450,000 Value ($000) $317 Avg Close — Range —
Q1 2016
Shares 1,000,000 Value ($000) $910 Avg Close — Range —
Q4 2015
Shares 1,000,000 Value ($000) $1,110 Avg Close — Range —