KALA BIO INC

Ticker: KALA CUSIP: 483119202 Class: COMMON

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 26,900 Value ($000) $15 Avg Close $0.90 Range $0.51 - $1.91

Q4 2024

Shares 11,877 Value ($000) $82 Avg Close $6.30 Range $4.95 - $7.85

Q3 2024

Shares 14,005 Value ($000) $80 Avg Close $6.31 Range $5.12 - $7.88

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	26,900	$15	$0.90	$0.51 - $1.91
Q4 2024	11,877	$82	$6.30	$4.95 - $7.85
Q3 2024	14,005	$80	$6.31	$5.12 - $7.88