KALEIDO BIOSCIENCES INC

Ticker: KLDO CUSIP: 483347100 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021

Shares 46,000 Value ($000) $342 Avg Close $7.09 Range $5.71 - $9.47

Q1 2021

Shares 97,100 Value ($000) $787 Avg Close $10.89 Range $7.00 - $20.50

Q3 2020

Shares 10,300 Value ($000) $114 Avg Close $6.93 Range $5.04 - $11.89

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2021	46,000	$342	$7.09	$5.71 - $9.47
Q1 2021	97,100	$787	$10.89	$7.00 - $20.50
Q3 2020	10,300	$114	$6.93	$5.04 - $11.89