KARYOPHARM THERAPEUTICS INC

CUSIP: 48576U106 Class: Common Stock

ESSEX INVESTMENT MANAGEMENT CO LLC's Holding History (CIK: 0000201772)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 55,793 Value ($000) $524 Avg Close — Range —
Q4 2013
Shares 38,811 Value ($000) $890 Avg Close — Range —