KARYOPHARM THERAPEUTICS INC

CUSIP: 48576U106 Class: Common Stock

Itau Unibanco Holding S.A.'s Holding History (CIK: 0001132597)

Note: Option positions (PUT/CALL) are excluded.

Q3 2019
Shares 1,438 Value ($000) $9 Avg Close — Range —
Q2 2019
Shares 1,438 Value ($000) $9 Avg Close — Range —
Q1 2019
Shares 2,645 Value ($000) $24 Avg Close — Range —
Q4 2018
Shares 2,645 Value ($000) $24 Avg Close — Range —
Q3 2018
Shares 2,597 Value ($000) $44 Avg Close — Range —
Q2 2018
Shares 2,670 Value ($000) $45 Avg Close — Range —
Q1 2018
Shares 3,490 Value ($000) $47 Avg Close — Range —
Q4 2017
Shares 962 Value ($000) $9 Avg Close — Range —
Q3 2017
Shares 843 Value ($000) $29 Avg Close — Range —
Q2 2017
Shares 2,901 Value ($000) $26 Avg Close — Range —
Q1 2017
Shares 290 Value ($000) $4 Avg Close — Range —