KARYOPHARM THERAPEUTICS INC

CUSIP: 48576U106 Class: Common Stock

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2017
Shares 216,990 Value ($000) $2,083 Avg Close — Range —
Q3 2017
Shares 216,990 Value ($000) $2,383 Avg Close — Range —
Q2 2017
Shares 216,990 Value ($000) $1,964 Avg Close — Range —
Q1 2017
Shares 216,990 Value ($000) $2,786 Avg Close — Range —
Q4 2016
Shares 216,990 Value ($000) $2,040 Avg Close — Range —
Q3 2016
Shares 216,990 Value ($000) $2,111 Avg Close — Range —
Q2 2016
Shares 216,990 Value ($000) $1,456 Avg Close — Range —
Q1 2016
Shares 216,990 Value ($000) $1,936 Avg Close — Range —
Q4 2015
Shares 216,990 Value ($000) $2,875 Avg Close — Range —
Q3 2015
Shares 216,990 Value ($000) $2,285 Avg Close — Range —
Q2 2015
Shares 216,990 Value ($000) $5,904 Avg Close — Range —
Q1 2015
Shares 216,990 Value ($000) $6,642 Avg Close — Range —
Q4 2014
Shares 94,095 Value ($000) $3,522 Avg Close — Range —
Q3 2014
Shares 94,095 Value ($000) $3,288 Avg Close — Range —
Q2 2014
Shares 94,095 Value ($000) $4,380 Avg Close — Range —
Q1 2014
Shares 59,095 Value ($000) $1,825 Avg Close — Range —
Q4 2013
Shares 61,330 Value ($000) $1,406 Avg Close — Range —