KARYOPHARM THERAPEUTICS INC

CUSIP: 48576U106 Class: Common Stock

SECTORAL ASSET MANAGEMENT INC's Holding History (CIK: 0001274413)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 712,968 Value ($000) $7,508 Avg Close — Range —
Q2 2015
Shares 712,968 Value ($000) $19,400 Avg Close — Range —
Q1 2015
Shares 707,268 Value ($000) $21,649 Avg Close — Range —
Q4 2014
Shares 529,920 Value ($000) $19,835 Avg Close — Range —
Q3 2014
Shares 488,342 Value ($000) $17,063 Avg Close — Range —
Q2 2014
Shares 268,540 Value ($000) $12,501 Avg Close — Range —
Q4 2013
Shares 35,000 Value ($000) $802 Avg Close — Range —