KARYOPHARM THERAPEUTICS INC

CUSIP: 48576U106 Class: Common Stock

PFM Health Sciences, LP's Holding History (CIK: 0001442756)

Note: Option positions (PUT/CALL) are excluded.

Q2 2015
Shares 821,594 Value ($000) $22,356 Avg Close — Range —
Q1 2015
Shares 1,124,056 Value ($000) $34,407 Avg Close — Range —
Q4 2014
Shares 850,337 Value ($000) $31,828 Avg Close — Range —
Q3 2014
Shares 1,125,854 Value ($000) $39,337 Avg Close — Range —
Q2 2014
Shares 662,842 Value ($000) $30,855 Avg Close — Range —
Q1 2014
Shares 309,592 Value ($000) $9,563 Avg Close — Range —
Q4 2013
Shares 889,520 Value ($000) $19,785 Avg Close — Range —