KARYOPHARM THERAPEUTICS INC

CUSIP: 48576U106 Class: Common Stock

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q4 2014
Shares 30,000 Value ($000) $1,123 Avg Close — Range —
Q3 2014
Shares 30,000 Value ($000) $1,048 Avg Close — Range —
Q2 2014
Shares 30,000 Value ($000) $1,397 Avg Close — Range —
Q1 2014
Shares 67,800 Value ($000) $2,094 Avg Close — Range —
Q4 2013
Shares 29,600 Value ($000) $678 Avg Close — Range —