KARYOPHARM THERAPEUTICS INC

CUSIP: 48576U106 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q1 2024
Shares 10,208 Value ($000) $15 Avg Close — Range —
Q4 2023
Shares 19,586 Value ($000) $17 Avg Close — Range —
Q2 2023
Shares 13,480 Value ($000) $24 Avg Close — Range —