KARYOPHARM THERAPEUTICS INC

CUSIP: 48576U106 Class: Common Stock

Vontobel Holding Ltd.'s Holding History (CIK: 0001588340)

Note: Option positions (PUT/CALL) are excluded.

Q3 2021
Shares 30,000 Value ($000) $175 Avg Close — Range —
Q2 2021
Shares 30,000 Value ($000) $310 Avg Close — Range —
Q1 2021
Shares 30,000 Value ($000) $316 Avg Close — Range —
Q4 2020
Shares 23,475 Value ($000) $363 Avg Close — Range —