KERYX BIOPHARMACEUTICALS INC

CUSIP: 492515101 Class: COMMON STOCK

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 67,981 Value ($000) $231 Avg Close — Range —
Q2 2018
Shares 77,085 Value ($000) $290 Avg Close — Range —
Q1 2018
Shares 73,150 Value ($000) $299 Avg Close — Range —
Q4 2017
Shares 75,179 Value ($000) $349 Avg Close — Range —
Q3 2017
Shares 73,531 Value ($000) $522 Avg Close — Range —
Q2 2017
Shares 66,161 Value ($000) $477 Avg Close — Range —
Q1 2017
Shares 63,597 Value ($000) $392 Avg Close — Range —
Q4 2016
Shares 55,959 Value ($000) $328 Avg Close — Range —
Q3 2016
Shares 56,290 Value ($000) $299 Avg Close — Range —
Q2 2016
Shares 56,181 Value ($000) $372 Avg Close — Range —
Q1 2016
Shares 69,626 Value ($000) $328 Avg Close — Range —
Q4 2015
Shares 68,766 Value ($000) $348 Avg Close — Range —
Q3 2015
Shares 68,766 Value ($000) $242 Avg Close — Range —
Q2 2015
Shares 279,020 Value ($000) $2,785 Avg Close — Range —
Q1 2015
Shares 279,212 Value ($000) $3,555 Avg Close — Range —
Q4 2014
Shares 230,317 Value ($000) $3,259 Avg Close — Range —
Q3 2014
Shares 258,898 Value ($000) $3,560 Avg Close — Range —
Q2 2014
Shares 248,635 Value ($000) $3,824 Avg Close — Range —
Q1 2014
Shares 66,427 Value ($000) $1,132 Avg Close — Range —
Q4 2013
Shares 61,888 Value ($000) $801 Avg Close — Range —
Q3 2013
Shares 59,911 Value ($000) $605 Avg Close — Range —
Q2 2013
Shares 58,913 Value ($000) $440 Avg Close — Range —