KYTHERA BIOPHARMACEUTICALS I

CUSIP: 501570105 Class: COM

ESSEX INVESTMENT MANAGEMENT CO LLC's Holding History (CIK: 0000201772)

Note: Option positions (PUT/CALL) are excluded.

Q3 2013
Shares 5,043 Value ($000) $230 Avg Close — Range —
Q2 2013
Shares 8,118 Value ($000) $220 Avg Close — Range —