KYTHERA BIOPHARMACEUTICALS I

CUSIP: 501570105 Class: COM

GREAT WEST LIFE ASSURANCE CO /CAN/'s Holding History (CIK: 0001046192)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 1,691 Value ($000) $127 Avg Close — Range —
Q2 2015
Shares 1,691 Value ($000) $127 Avg Close — Range —
Q1 2015
Shares 1,691 Value ($000) $85 Avg Close — Range —