KYTHERA BIOPHARMACEUTICALS I

CUSIP: 501570105 Class: COM

SIGNATURE ESTATE & INVESTMENT ADVISORS LLC's Holding History (CIK: 0001079935)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 2,388 Value ($000) $179 Avg Close — Range —
Q2 2015
Shares 2,388 Value ($000) $180 Avg Close — Range —
Q1 2015
Shares 4,388 Value ($000) $220 Avg Close — Range —
Q4 2014
Shares 4,388 Value ($000) $152 Avg Close — Range —
Q3 2014
Shares 4,388 Value ($000) $144 Avg Close — Range —
Q3 2013
Shares 4,388 Value ($000) $200 Avg Close — Range —