KYTHERA BIOPHARMACEUTICALS I

CUSIP: 501570105 Class: COM

SIMPLEX TRADING, LLC's Holding History (CIK: 0001488542)

Note: Option positions (PUT/CALL) are excluded.

Q3 2015
Shares 1,485 Value ($000) $111 Avg Close — Range —
Q4 2014
Shares 3,650 Value ($000) $127 Avg Close — Range —