LEXICON PHARMACEUTICALS INC

CUSIP: 528872104 Class: CMN

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 182,133 Value ($000) $172 Avg Close — Range —
Q4 2014
Shares 172,351 Value ($000) $157 Avg Close — Range —
Q3 2014
Shares 159,797 Value ($000) $225 Avg Close — Range —
Q2 2014
Shares 157,861 Value ($000) $254 Avg Close — Range —
Q1 2014
Shares 184,091 Value ($000) $318 Avg Close — Range —
Q4 2013
Shares 181,598 Value ($000) $326 Avg Close — Range —
Q3 2013
Shares 181,585 Value ($000) $431 Avg Close — Range —
Q2 2013
Shares 190,480 Value ($000) $413 Avg Close — Range —