LEXICON PHARMACEUTICALS INC

CUSIP: 528872104 Class: CMN

Artal Group S.A.'s Holding History (CIK: 0001053906)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 402,625,866 Value ($000) $378,492 Avg Close — Range —
Q4 2014
Shares 402,625,866 Value ($000) $366,389 Avg Close — Range —
Q3 2014
Shares 253,372,135 Value ($000) $357,255 Avg Close — Range —
Q2 2014
Shares 253,372,135 Value ($000) $407,929 Avg Close — Range —
Q1 2014
Shares 253,372,135 Value ($000) $438,334 Avg Close — Range —
Q4 2013
Shares 253,372,135 Value ($000) $456,064 Avg Close — Range —
Q3 2013
Shares 253,372,135 Value ($000) $603,026 Avg Close — Range —
Q2 2013
Shares 253,372,135 Value ($000) $549,818 Avg Close — Range —