LIGHTWAVE LOGIC INC

Ticker: LWLG CUSIP: 532275104 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 138,050 Value ($000) $447 Avg Close $4.44 Range $2.84 - $6.26

Q2 2024

Shares 21,791 Value ($000) $65 Avg Close $3.65 Range $2.44 - $4.82

Q1 2023

Shares 27,316 Value ($000) $143 Avg Close $5.58 Range $4.03 - $7.45

Q4 2022

Shares 117,985 Value ($000) $509 Avg Close $7.10 Range $3.91 - $9.64

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	138,050	$447	$4.44	$2.84 - $6.26
Q2 2024	21,791	$65	$3.65	$2.44 - $4.82
Q1 2023	27,316	$143	$5.58	$4.03 - $7.45
Q4 2022	117,985	$509	$7.10	$3.91 - $9.64