LILLY ELI & CO

Ticker: LLY CUSIP: 532457108 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 13,068 Value ($000) $14,044 Avg Close $955.55 Range $762.18 - $1111.99

Q3 2025

Shares 200,906 Value ($000) $153,291 Avg Close $742.24 Range $621.50 - $817.22

Q2 2025

Shares 73,749 Value ($000) $57,490 Avg Close $773.40 Range $673.24 - $897.36

Q1 2025

Shares 15,733 Value ($000) $12,994 Avg Close $826.69 Range $719.64 - $930.30

Q4 2024

Shares 322,690 Value ($000) $249,117 Avg Close $821.14 Range $706.13 - $928.52

Q3 2024

Shares 199,736 Value ($000) $176,954 Avg Close $890.31 Range $739.75 - $963.73

Q2 2024

Shares 225,780 Value ($000) $204,417 Avg Close $790.93 Range $709.60 - $905.99

Q1 2024

Shares 71,621 Value ($000) $55,718 Avg Close $702.49 Range $571.04 - $791.08

Q4 2023

Shares 99,196 Value ($000) $57,823 Avg Close $575.10 Range $508.48 - $620.11

Q3 2023

Shares 432,734 Value ($000) $232,434 Avg Close $506.78 Range $426.62 - $592.42

Q4 2022

Shares 294,302 Value ($000) $107,667 Avg Close $345.79 Range $308.75 - $366.44

Q1 2022

Shares 440,736 Value ($000) $126,214 Avg Close $248.50 Range $224.15 - $285.70

Q4 2021

Shares 406,419 Value ($000) $112,261 Avg Close $243.85 Range $215.31 - $273.50

Q3 2021

Shares 996,910 Value ($000) $230,336 Avg Close $236.66 Range $211.45 - $264.90

Q3 2020

Shares 130,213 Value ($000) $19,274 Avg Close $145.78 Range $136.96 - $160.43

Q2 2020

Shares 5,938 Value ($000) $975 Avg Close $143.90 Range $124.36 - $157.31

Q1 2020

Shares 497,184 Value ($000) $68,969 Avg Close $128.17 Range $109.47 - $137.57

Q4 2019

Shares 458,044 Value ($000) $60,201 Avg Close $107.55 Range $93.76 - $127.45

Q3 2019

Shares 171,126 Value ($000) $19,137 Avg Close $102.71 Range $96.72 - $108.44

Q2 2019

Shares 272,337 Value ($000) $30,172 Avg Close $108.01 Range $101.20 - $120.15

Q4 2018

Shares 26,947 Value ($000) $3,118 Avg Close $101.37 Range $94.30 - $109.03

Q3 2018

Shares 1,202,250 Value ($000) $129,013 Avg Close $90.28 Range $76.26 - $97.62

Q2 2018

Shares 590,797 Value ($000) $50,413 Avg Close $73.70 Range $67.41 - $78.56

Q1 2018

Shares 1,841,708 Value ($000) $142,493 Avg Close $71.71 Range $65.40 - $78.39

Q4 2017

Shares 173,430 Value ($000) $14,648 Avg Close $75.28 Range $72.07 - $79.07

Q4 2016

Shares 116,791 Value ($000) $8,590 Avg Close $64.22 Range $55.51 - $71.52

Q2 2016

Shares 409,670 Value ($000) $32,262 Avg Close $64.09 Range $60.67 - $67.29

Q1 2016

Shares 1,407,632 Value ($000) $101,364 Avg Close $63.98 Range $57.57 - $71.93

Q3 2015

Shares 236,798 Value ($000) $19,818 Avg Close $70.47 Range $65.09 - $77.71

Q2 2015

Shares 16,728 Value ($000) $1,397 Avg Close $63.20 Range $58.00 - $72.58

Q3 2014

Shares 45,559 Value ($000) $2,955 Avg Close $51.38 Range $48.59 - $54.68

Q4 2013

Shares 2,381,491 Value ($000) $121,457 Avg Close $39.58 Range $37.37 - $40.99

Q3 2013

Shares 1,921,405 Value ($000) $96,704 Avg Close $40.99 Range $38.39 - $44.43

Q2 2013

Shares 1,589,982 Value ($000) $78,100 Avg Close $42.21 Range $37.93 - $45.11

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	13,068	$14,044	$955.55	$762.18 - $1111.99
Q3 2025	200,906	$153,291	$742.24	$621.50 - $817.22
Q2 2025	73,749	$57,490	$773.40	$673.24 - $897.36
Q1 2025	15,733	$12,994	$826.69	$719.64 - $930.30
Q4 2024	322,690	$249,117	$821.14	$706.13 - $928.52
Q3 2024	199,736	$176,954	$890.31	$739.75 - $963.73
Q2 2024	225,780	$204,417	$790.93	$709.60 - $905.99
Q1 2024	71,621	$55,718	$702.49	$571.04 - $791.08
Q4 2023	99,196	$57,823	$575.10	$508.48 - $620.11
Q3 2023	432,734	$232,434	$506.78	$426.62 - $592.42
Q4 2022	294,302	$107,667	$345.79	$308.75 - $366.44
Q1 2022	440,736	$126,214	$248.50	$224.15 - $285.70
Q4 2021	406,419	$112,261	$243.85	$215.31 - $273.50
Q3 2021	996,910	$230,336	$236.66	$211.45 - $264.90
Q3 2020	130,213	$19,274	$145.78	$136.96 - $160.43
Q2 2020	5,938	$975	$143.90	$124.36 - $157.31
Q1 2020	497,184	$68,969	$128.17	$109.47 - $137.57
Q4 2019	458,044	$60,201	$107.55	$93.76 - $127.45
Q3 2019	171,126	$19,137	$102.71	$96.72 - $108.44
Q2 2019	272,337	$30,172	$108.01	$101.20 - $120.15
Q4 2018	26,947	$3,118	$101.37	$94.30 - $109.03
Q3 2018	1,202,250	$129,013	$90.28	$76.26 - $97.62
Q2 2018	590,797	$50,413	$73.70	$67.41 - $78.56
Q1 2018	1,841,708	$142,493	$71.71	$65.40 - $78.39
Q4 2017	173,430	$14,648	$75.28	$72.07 - $79.07
Q4 2016	116,791	$8,590	$64.22	$55.51 - $71.52
Q2 2016	409,670	$32,262	$64.09	$60.67 - $67.29
Q1 2016	1,407,632	$101,364	$63.98	$57.57 - $71.93
Q3 2015	236,798	$19,818	$70.47	$65.09 - $77.71
Q2 2015	16,728	$1,397	$63.20	$58.00 - $72.58
Q3 2014	45,559	$2,955	$51.38	$48.59 - $54.68
Q4 2013	2,381,491	$121,457	$39.58	$37.37 - $40.99
Q3 2013	1,921,405	$96,704	$40.99	$38.39 - $44.43
Q2 2013	1,589,982	$78,100	$42.21	$37.93 - $45.11