LIXTE BIOTECHNOLOGY HLDGS IN

CUSIP: 539319202 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q1 2023
Shares 24,901 Value ($000) $21 Avg Close — Range —
Q4 2022
Shares 19,874 Value ($000) $10 Avg Close — Range —
Q3 2022
Shares 21,274 Value ($000) $12 Avg Close — Range —
Q2 2022
Shares 16,948 Value ($000) $13 Avg Close — Range —