LYRA THERAPEUTICS INC

CUSIP: 55234L105 Class: Common Stock

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2023
Shares 12,765 Value ($000) $67 Avg Close — Range —
Q3 2022
Shares 12,772 Value ($000) $64 Avg Close — Range —