MACROGENICS INC

Ticker: MGNX CUSIP: 556099109 Class: COM

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 999,474 Value ($000) $1,609 Avg Close $1.57 Range $1.29 - $2.15

Q3 2025

Shares 437,091 Value ($000) $734 Avg Close $1.62 Range $1.19 - $2.22

Q2 2025

Shares 407,288 Value ($000) $493 Avg Close $1.45 Range $0.99 - $2.17

Q1 2025

Shares 654,898 Value ($000) $832 Avg Close $2.61 Range $1.17 - $3.60

Q4 2024

Shares 860,745 Value ($000) $2,797 Avg Close $3.60 Range $3.08 - $5.10

Q3 2024

Shares 883,369 Value ($000) $2,906 Avg Close $3.90 Range $2.95 - $5.77

Q2 2024

Shares 1,223,993 Value ($000) $5,202 Avg Close $9.74 Range $3.14 - $19.54

Q1 2024

Shares 13,363 Value ($000) $197 Avg Close $15.11 Range $9.33 - $21.88

Q4 2023

Shares 51,063 Value ($000) $491 Avg Close $6.91 Range $4.29 - $10.74

Q3 2023

Shares 52,563 Value ($000) $245 Avg Close $4.98 Range $4.44 - $6.45

Q2 2023

Shares 309,642 Value ($000) $1,657 Avg Close $6.17 Range $4.56 - $7.90

Q1 2023

Shares 679,755 Value ($000) $4,874 Avg Close $6.02 Range $4.53 - $7.49

Q4 2022

Shares 701,343 Value ($000) $4,706 Avg Close $5.48 Range $3.15 - $7.57

Q3 2022

Shares 393,683 Value ($000) $1,362 Avg Close $3.83 Range $2.91 - $5.41

Q2 2022

Shares 992,567 Value ($000) $2,928 Avg Close $5.26 Range $2.13 - $10.20

Q1 2022

Shares 360,694 Value ($000) $3,178 Avg Close $11.04 Range $7.91 - $17.20

Q4 2021

Shares 15,648 Value ($000) $251 Avg Close $18.82 Range $15.72 - $22.68

Q1 2021

Shares 44,625 Value ($000) $1,421 Avg Close $24.28 Range $18.16 - $33.39

Q4 2020

Shares 128,568 Value ($000) $2,939 Avg Close $23.02 Range $18.68 - $28.19

Q3 2020

Shares 163,726 Value ($000) $4,124 Avg Close $27.30 Range $23.80 - $32.18

Q2 2020

Shares 166,302 Value ($000) $4,643 Avg Close $17.37 Range $5.00 - $29.80

Q1 2020

Shares 83,039 Value ($000) $483 Avg Close $9.08 Range $4.04 - $12.55

Q4 2019

Shares 132,108 Value ($000) $1,437 Avg Close $9.90 Range $7.42 - $13.13

Q2 2019

Shares 12,148 Value ($000) $206 Avg Close $17.18 Range $13.94 - $19.80

Q1 2019

Shares 63,798 Value ($000) $1,147 Avg Close $17.29 Range $9.87 - $32.32

Q4 2018

Shares 57,416 Value ($000) $729 Avg Close $16.77 Range $11.16 - $21.87

Q2 2017

Shares 18,898 Value ($000) $331 Avg Close $19.07 Range $16.63 - $22.31

Q4 2016

Shares 21,560 Value ($000) $441 Avg Close $25.17 Range $18.22 - $31.85

Q1 2016

Shares 17,317 Value ($000) $325 Avg Close $19.04 Range $14.84 - $30.66

Q4 2014

Shares 7,800 Value ($000) $274 Avg Close $24.93 Range $17.31 - $39.90

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	999,474	$1,609	$1.57	$1.29 - $2.15
Q3 2025	437,091	$734	$1.62	$1.19 - $2.22
Q2 2025	407,288	$493	$1.45	$0.99 - $2.17
Q1 2025	654,898	$832	$2.61	$1.17 - $3.60
Q4 2024	860,745	$2,797	$3.60	$3.08 - $5.10
Q3 2024	883,369	$2,906	$3.90	$2.95 - $5.77
Q2 2024	1,223,993	$5,202	$9.74	$3.14 - $19.54
Q1 2024	13,363	$197	$15.11	$9.33 - $21.88
Q4 2023	51,063	$491	$6.91	$4.29 - $10.74
Q3 2023	52,563	$245	$4.98	$4.44 - $6.45
Q2 2023	309,642	$1,657	$6.17	$4.56 - $7.90
Q1 2023	679,755	$4,874	$6.02	$4.53 - $7.49
Q4 2022	701,343	$4,706	$5.48	$3.15 - $7.57
Q3 2022	393,683	$1,362	$3.83	$2.91 - $5.41
Q2 2022	992,567	$2,928	$5.26	$2.13 - $10.20
Q1 2022	360,694	$3,178	$11.04	$7.91 - $17.20
Q4 2021	15,648	$251	$18.82	$15.72 - $22.68
Q1 2021	44,625	$1,421	$24.28	$18.16 - $33.39
Q4 2020	128,568	$2,939	$23.02	$18.68 - $28.19
Q3 2020	163,726	$4,124	$27.30	$23.80 - $32.18
Q2 2020	166,302	$4,643	$17.37	$5.00 - $29.80
Q1 2020	83,039	$483	$9.08	$4.04 - $12.55
Q4 2019	132,108	$1,437	$9.90	$7.42 - $13.13
Q2 2019	12,148	$206	$17.18	$13.94 - $19.80
Q1 2019	63,798	$1,147	$17.29	$9.87 - $32.32
Q4 2018	57,416	$729	$16.77	$11.16 - $21.87
Q2 2017	18,898	$331	$19.07	$16.63 - $22.31
Q4 2016	21,560	$441	$25.17	$18.22 - $31.85
Q1 2016	17,317	$325	$19.04	$14.84 - $30.66
Q4 2014	7,800	$274	$24.93	$17.31 - $39.90