MAST THERAPEUTICS INC

CUSIP: 576314108 Class: COM

BAKER BROS. ADVISORS LP's Holding History (CIK: 0001263508)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 8,584,051 Value ($000) $944 Avg Close — Range —
Q2 2016
Shares 3,868,026 Value ($000) $1,818 Avg Close — Range —
Q1 2016
Shares 4,797,442 Value ($000) $1,309 Avg Close — Range —
Q4 2015
Shares 4,797,442 Value ($000) $2,016 Avg Close — Range —
Q3 2015
Shares 4,707,464 Value ($000) $2,730 Avg Close — Range —
Q2 2015
Shares 4,707,464 Value ($000) $2,307 Avg Close — Range —
Q1 2015
Shares 4,707,464 Value ($000) $2,283 Avg Close — Range —
Q4 2014
Shares 4,774,434 Value ($000) $2,674 Avg Close — Range —
Q3 2014
Shares 3,000,000 Value ($000) $1,671 Avg Close — Range —
Q1 2014
Shares 3,000,000 Value ($000) $2,040 Avg Close — Range —