MEDICINES CO

CUSIP: 584688105 Class: COM

LOOMIS SAYLES & CO L P's Holding History (CIK: 0000312348)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 367,190 Value ($000) $12,462 Avg Close — Range —
Q3 2016
Shares 346,546 Value ($000) $13,079 Avg Close — Range —
Q2 2016
Shares 60 Value ($000) $2 Avg Close — Range —
Q1 2016
Shares 60 Value ($000) $2 Avg Close — Range —
Q1 2014
Shares 512,429 Value ($000) $14,563 Avg Close — Range —
Q4 2013
Shares 312,695 Value ($000) $12,077 Avg Close — Range —