MEDICINES CO

CUSIP: 584688105 Class: COM

CAISSE DE DEPOT ET PLACEMENT DU QUEBEC's Holding History (CIK: 0000898286)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 190,000 Value ($000) $5,324 Avg Close — Range —
Q4 2014
Shares 125,000 Value ($000) $3,459 Avg Close — Range —
Q2 2014
Shares 600,000 Value ($000) $17,436 Avg Close — Range —