MEDICINES CO

CUSIP: 584688105 Class: COM

VIRGINIA RETIREMENT SYSTEMS ET AL's Holding History (CIK: 0001005354)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 53,500 Value ($000) $1,762 Avg Close — Range —
Q4 2017
Shares 40,000 Value ($000) $1,094 Avg Close — Range —