MEDICINES CO

CUSIP: 584688105 Class: COM

Artal Group S.A.'s Holding History (CIK: 0001053906)

Note: Option positions (PUT/CALL) are excluded.

Q3 2019
Shares 1,400,000 Value ($000) $70,000 Avg Close — Range —
Q2 2019
Shares 1,000,000 Value ($000) $36,470 Avg Close — Range —
Q1 2019
Shares 700,000 Value ($000) $19,565 Avg Close — Range —
Q4 2018
Shares 400,000 Value ($000) $7,656 Avg Close — Range —
Q3 2018
Shares 400,000 Value ($000) $11,964 Avg Close — Range —
Q2 2018
Shares 400,000 Value ($000) $14,680 Avg Close — Range —
Q1 2018
Shares 200,000 Value ($000) $6,588 Avg Close — Range —
Q4 2017
Shares 200,000 Value ($000) $5,468 Avg Close — Range —
Q3 2017
Shares 300,000 Value ($000) $11,112 Avg Close — Range —
Q2 2017
Shares 350,000 Value ($000) $13,304 Avg Close — Range —
Q1 2017
Shares 100,000 Value ($000) $4,890 Avg Close — Range —
Q4 2016
Shares 50,000 Value ($000) $1,697 Avg Close — Range —