MEDICINES CO

CUSIP: 584688105 Class: COM

Asset Management One Co., Ltd.'s Holding History (CIK: 0001068855)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 8,656 Value ($000) $294 Avg Close — Range —
Q3 2016
Shares 10,466 Value ($000) $398 Avg Close — Range —
Q2 2016
Shares 9,457 Value ($000) $318 Avg Close — Range —