MEDICINES CO

CUSIP: 584688105 Class: COM

NEXT CENTURY GROWTH INVESTORS LLC's Holding History (CIK: 0001134007)

Note: Option positions (PUT/CALL) are excluded.

Q1 2014
Shares 215,678 Value ($000) $6,129 Avg Close — Range —
Q4 2013
Shares 235,764 Value ($000) $9,105 Avg Close — Range —