MEDICINES CO

CUSIP: 584688105 Class: COM

RA CAPITAL MANAGEMENT, L.P.'s Holding History (CIK: 0001346824)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 79,899 Value ($000) $3,907 Avg Close — Range —
Q4 2016
Shares 79,899 Value ($000) $2,712 Avg Close — Range —
Q2 2015
Shares 705,925 Value ($000) $20,197 Avg Close — Range —