MEDICINES CO

CUSIP: 584688105 Class: COM

TWIN FOCUS CAPITAL PARTNERS, LLC's Holding History (CIK: 0001387761)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 26,000 Value ($000) $856 Avg Close — Range —
Q4 2017
Shares 26,000 Value ($000) $711 Avg Close — Range —
Q3 2017
Shares 26,000 Value ($000) $963 Avg Close — Range —
Q2 2017
Shares 26,000 Value ($000) $988 Avg Close — Range —
Q1 2017
Shares 26,000 Value ($000) $1,271 Avg Close — Range —
Q4 2016
Shares 26,000 Value ($000) $882 Avg Close — Range —
Q3 2016
Shares 26,000 Value ($000) $981 Avg Close — Range —
Q2 2016
Shares 26,000 Value ($000) $874 Avg Close — Range —
Q1 2016
Shares 26,000 Value ($000) $826 Avg Close — Range —
Q4 2015
Shares 26,000 Value ($000) $971 Avg Close — Range —