MEDICINES CO

CUSIP: 584688105 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q4 2019
Shares 211,301 Value ($000) $17,948 Avg Close — Range —
Q3 2019
Shares 53,301 Value ($000) $2,665 Avg Close — Range —
Q2 2019
Shares 34,001 Value ($000) $1,240 Avg Close — Range —
Q2 2018
Shares 13,600 Value ($000) $499 Avg Close — Range —
Q1 2015
Shares 8,501 Value ($000) $238 Avg Close — Range —
Q4 2014
Shares 21,701 Value ($000) $600 Avg Close — Range —
Q2 2014
Shares 7,101 Value ($000) $206 Avg Close — Range —