MEDICINES CO

CUSIP: 584688105 Class: COM

FOX RUN MANAGEMENT, L.L.C.'s Holding History (CIK: 0001533457)

Note: Option positions (PUT/CALL) are excluded.

Q3 2017
Shares 15,800 Value ($000) $585 Avg Close — Range —
Q1 2016
Shares 13,600 Value ($000) $432 Avg Close — Range —