MEDICINES CO

CUSIP: 584688AC9 Class: 1.38% 06/01/17

ADVENT CAPITAL MANAGEMENT /DE/'s Holding History (CIK: 0001097278)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 95,000 Value ($000) $139 Avg Close — Range —
Q4 2016
Shares 95,000 Value ($000) $139 Avg Close — Range —
Q3 2016
Shares 95,000 Value ($000) $139 Avg Close — Range —
Q2 2016
Shares 95,000 Value ($000) $139 Avg Close — Range —
Q1 2016
Shares 95,000 Value ($000) $139 Avg Close — Range —
Q4 2015
Shares 102,000 Value ($000) $149 Avg Close — Range —
Q3 2015
Shares 140,000 Value ($000) $204 Avg Close — Range —
Q2 2015
Shares 20,402,000 Value ($000) $24,356 Avg Close — Range —
Q1 2015
Shares 22,078,000 Value ($000) $26,288 Avg Close — Range —
Q4 2014
Shares 13,541,000 Value ($000) $15,786 Avg Close — Range —
Q3 2014
Shares 8,714,000 Value ($000) $9,307 Avg Close — Range —
Q2 2014
Shares 8,714,000 Value ($000) $9,703 Avg Close — Range —
Q1 2014
Shares 11,215,000 Value ($000) $13,745 Avg Close — Range —
Q4 2013
Shares 10,028,000 Value ($000) $15,071 Avg Close — Range —