MEDICINES CO

CUSIP: 584688AC9 Class: 1.38% 06/01/17

CITADEL ADVISORS LLC's Holding History (CIK: 0001423053)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 15,345,000 Value ($000) $26,938 Avg Close — Range —
Q4 2016
Shares 8,345,000 Value ($000) $11,075 Avg Close — Range —
Q3 2016
Shares 8,345,000 Value ($000) $12,087 Avg Close — Range —
Q2 2016
Shares 7,725,000 Value ($000) $10,535 Avg Close — Range —
Q1 2016
Shares 65,000,000 Value ($000) $82,768 Avg Close — Range —
Q4 2015
Shares 67,000,000 Value ($000) $95,881 Avg Close — Range —
Q3 2015
Shares 50,000,000 Value ($000) $72,648 Avg Close — Range —
Q2 2015
Shares 31,916,000 Value ($000) $38,152 Avg Close — Range —
Q1 2015
Shares 45,000,000 Value ($000) $53,453 Avg Close — Range —
Q4 2014
Shares 66,526,000 Value ($000) $77,572 Avg Close — Range —
Q3 2014
Shares 60,526,000 Value ($000) $64,528 Avg Close — Range —
Q2 2014
Shares 68,540,000 Value ($000) $84,415 Avg Close — Range —
Q1 2014
Shares 60,000,000 Value ($000) $73,445 Avg Close — Range —
Q4 2013
Shares 49,400,000 Value ($000) $74,128 Avg Close — Range —