MELINTA THERAPEUTICS INC

CUSIP: 58549G100 Class: COMMON STOCK

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 12,608 Value ($000) $10 Avg Close — Range —
Q3 2018
Shares 15,091 Value ($000) $60 Avg Close — Range —
Q2 2018
Shares 910 Value ($000) $6 Avg Close — Range —
Q1 2018
Shares 13,046 Value ($000) $97 Avg Close — Range —
Q4 2017
Shares 8,398 Value ($000) $133 Avg Close — Range —