MILESTONE PHARMACEUTICALS IN

Ticker: MIST CUSIP: 59935V107 Class: COM

Point72 Asset Management, L.P.'s Holding History (CIK: 0001603466)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 482,355 Value ($000) $974 Avg Close $2.15 Range $1.61 - $3.06

Q2 2023

Shares 232,659 Value ($000) $663 Avg Close $3.77 Range $2.73 - $4.49

Q1 2023

Shares 1,275,000 Value ($000) $5,024 Avg Close $3.66 Range $3.10 - $4.44

Q4 2022

Shares 875,000 Value ($000) $3,465 Avg Close $5.26 Range $3.39 - $9.72

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	482,355	$974	$2.15	$1.61 - $3.06
Q2 2023	232,659	$663	$3.77	$2.73 - $4.49
Q1 2023	1,275,000	$5,024	$3.66	$3.10 - $4.44
Q4 2022	875,000	$3,465	$5.26	$3.39 - $9.72