NRX PHARMACEUTICALS INC

Ticker: NRXP CUSIP: 629444209 Class: Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 17,436 Value ($000) $47 Avg Close $2.68 Range $1.96 - $3.84

Q3 2025

Shares 52,332 Value ($000) $173 Avg Close $2.86 Range $2.26 - $3.48

Q2 2025

Shares 31,452 Value ($000) $103 Avg Close $2.51 Range $1.58 - $3.83

Q1 2025

Shares 30,146 Value ($000) $62 Avg Close $2.82 Range $1.84 - $6.01

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	17,436	$47	$2.68	$1.96 - $3.84
Q3 2025	52,332	$173	$2.86	$2.26 - $3.48
Q2 2025	31,452	$103	$2.51	$1.58 - $3.83
Q1 2025	30,146	$62	$2.82	$1.84 - $6.01