NANOSPHERE INC

CUSIP: 63009F105 Class: COM

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q1 2015
Shares 44,945 Value ($000) $10 Avg Close — Range —
Q4 2014
Shares 349,991 Value ($000) $137 Avg Close — Range —