NANOSPHERE INC

CUSIP: 63009F105 Class: COM

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q2 2014
Shares 12,900 Value ($000) $20 Avg Close — Range —
Q1 2014
Shares 14,200 Value ($000) $31 Avg Close — Range —