NIGHTSTAR THERAPEUTICS PLC

CUSIP: 65413A101 Class: ADR

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 21,615 Value ($000) $548 Avg Close — Range —
Q3 2018
Shares 26,487 Value ($000) $541 Avg Close — Range —