NIGHTSTAR THERAPEUTICS PLC

CUSIP: 65413A101 Class: ADR

MARSHALL WACE, LLP's Holding History (CIK: 0001318757)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 8,973 Value ($000) $103 Avg Close — Range —
Q3 2018
Shares 58,996 Value ($000) $1,205 Avg Close — Range —