NIGHTSTAR THERAPEUTICS PLC

CUSIP: 65413A101 Class: ADR

Point72 Asset Management, L.P.'s Holding History (CIK: 0001603466)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 729,628 Value ($000) $18,511 Avg Close — Range —
Q4 2018
Shares 1,333,640 Value ($000) $15,364 Avg Close — Range —
Q3 2018
Shares 1,527,229 Value ($000) $31,201 Avg Close — Range —